College Football Odds, Tips, Predictions, Best Bets for Week 4, 2022: Proven Simulation like USC, Texas

No. 5 Clemson will face its first real test of the season when it travels to No. 21 Wake Forest on Saturday afternoon. The Tigers have won all three games by at least 20 points, while Wake Forest has had back-to-back wins over Vanderbilt and Liberty. Caesars Sportsbook ranked Clemson as a 7-point favorite in the latest Week 4 college football odds. Should you support the Tigers with your week 4 college football bets?

Another top week 4 college football matchup is the #11 Tennessee vs. #20 Florida matchup at 3:30 p.m. ET SEC on CBS. The Vols have never been favored by more than a touchdown against the Gators, but they are 10.5-point favorites in the latest week four college football spreads. Before you set any week 4 college football picks for this game or any other, you should definitely do it Check out the latest college football predictions from SportsLine’s advanced computer model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the last 6+ years, the proprietary computer model has generated a staggering win of more than $3,300 for $100 players on its top ratings College Football Picks against the spread. It goes into Week 4 of the 2022 college football season with a 51-43 run on all the top-flight college football spreads and money line picks going back to 2021. Anyone who has followed it has seen tremendous returns.

Now it has turned its attention to the last week 4 College football odds by Caesars and locked picks for every FBS matchup. Go here to see each selection.

The best college football predictions for week 4

One of the college picks the model is high on in Week 4: No. 22 Texas (-7) takes to the streets and covers against Texas Tech in a matchup at 3:30 p.m. ET in Lubbock. The Longhorns have had a rollercoaster ride over the past two weeks, but they’ve taken positives from both games. They almost pulled off an unlikely upset against leaders Alabama two weeks ago, easily closing the 21-point spread.

Texas looked set to fall victim to trap play last week as UTSA took a 17-7 lead in the second quarter. The Longhorns responded by scoring 34 of the next 37 points in a 41-20 win and covering the span as 13-point favorites. Junior running back Bijan Robinson rushed for 183 yards and three touchdowns against UTSA for an average of 9.2 yards per carry.

Robinson faces a Texas Tech defense, coming from back-to-back games against ranked opponents, allowing at least 27 points in both competitions. SportsLine’s model shows Robinson rushing for more than 110 yards and a touchdown on Saturday afternoon, which is one of the reasons Texas covers the spread in almost 60% of the simulations.

Another model college football pick, No. 7 USC (-6) hits the road and covers against Oregon State in a matchup at 9:30 p.m. ET in Corvallis. USC’s offense is already clicking on all cylinders, averaging 40+ points in all three games this season. The Trojans are led by sophomore quarterback Caleb Williams, who completed 74.4% of his passes for 874 yards and eight touchdowns.

Oregon State’s defense looked shaky at times earlier in the year, yielding 28 points to Montana State and 32 points to Fresno State. The Beavers will struggle to beat the Trojans hit by hit on Saturday night. SportsLine’s model is expecting another big day from Williams as he throws for more than 320 yards and three touchdowns in the latest simulations.

Oregon State quarterback Chance Nolan isn’t having nearly as much success in the simulations, completing just 16 of 26 passes for under 240 yards and one interception. The Trojans are one of the strongest picks of the week, covering distribution in more than 70% of the simulations. See what other teams the model likes here.

How to make college football picks for week 4

The model has also asked who wins and covers in every other FBS matchup in Week 4, and says a top 25 favorite will go down hard in one of the week’s biggest games. You can get every selection for every game only at SportsLine.

So what college football picks can you hit with confidence? And which top 25 favorite goes down hard? Then check out the latest college football odds below Visit SportsLine to see which teams are winning and cover the range, all from a proven computer model that has brought in over $3,300 in profits for the last 6+ seasonsand find out.

College Football Odds for Week 4 (via Caesars)

Check out full college football picks, odds and predictions for week 4 here

Friday 23 Sept

Virginia near Syracuse (-10, 53)

Featured Game | Syracuse Orange vs. Virginia Cavaliers

Nevada at Air Force (-24, 46.5)

Featured Game | Air Force Falcons vs. Nevada Wolf Pack

Boise State at UTEP (+16, 45.5)

Featured Game | UTEP Miners vs. Boise State Broncos

Saturday 24 Sept

Kent State in Georgia (-45, 62)

Maryland near Michigan (-17, 64.5)

Featured Game | Michigan Wolverines vs. Maryland Terrapins

Central Michigan at Penn State (-28, 63.5)

Featured Game | Penn State Nittany Lions vs. Central Michigan Chippewas

Duke in Kansas (-7, 65.5)

Featured Game | Kansas Jayhawks versus Duke Blue Devils

Clemson in the Watchwood (+7, 55.5)

Featured Game | Wake Forest Demon Deacons vs. Clemson Tigers

Baylor, Iowa (-2.5, 45.5)

Featured Game | Iowa State Cyclones vs Baylor Bears

Florida in Tennessee (-10.5, 62.5)

Featured Game | Tennessee Volunteers vs. Florida Gators

Notre Dame North Carolina (-1.5, 55)

Featured Game | North Carolina Tar Heels vs Notre Dame Fighting Irish

Texas at Texas Tech (+7, 61)

Featured Game | Texas Tech Red Raiders vs. Texas Longhorns

Tulsa at Ole Miss (-21.5, 65.5)

Featured Game | Ole Miss Rebels vs. Tulsa Golden Hurricane

Oregon in Washington State (+6.5, 57.5)

Featured Game | Washington State Cougars vs. Oregon Ducks

Northern Illinois near Kentucky (-26.5, 53)

Featured Game | Kentucky Wildcats vs. Northern Illinois Huskies

Arkansas at Texas A&M (-2, 48.5)

Featured Game | Texas A&M Aggies vs. Arkansas Razorbacks

Wisconsin, Ohio (-19, 57)

Featured Game | Ohio State Buckeyes vs. Wisconsin Badgers

Vanderbilt in Alabama (-40.5, 59)

State of Kansas in Oklahoma (-12.5, 53)

Featured Game | Oklahoma Sooners vs. Kansas State Wildcats

USC in the state of Oregon (+6, 70.5)

Featured Game | Oregon State Beavers vs. USC Trojans

Utah in the state of Arizona (+15.5, 54)

Featured Game | Arizona State Sun Devils vs. Utah Utes

Stanford at Washington (-13.5, 63.5)

Featured Game | Washington Huskies vs. Stanford Cardinal College Football Odds, Tips, Predictions, Best Bets for Week 4, 2022: Proven Simulation like USC, Texas

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