NFL Odds, Lines, Tips, Spreads, Best Bets, Predictions for Week 1, 2022: Model Loving Vikings, Colts

The Week 1 NFL schedule is packed with revenge plays, from Baker Mayfield versus the Browns to Russell Wilson returning to Seattle. Jaguars vs. Commanders is also a rematch game as Washington quarterback Carson Wentz meets former coach Doug Pederson. It will be the first matchup between Wentz and Pederson since the two left Philadelphia, and Washington is a three-point favorite in the latest NFL Week 1 odds at Caesars Sportsbook. This game is among the seven NFL spreads with a field goal or less. On the other hand, only one game, Colts vs. Texans (+8), has a line of more than a touchdown in the NFL Vegas odds. All Week 1 NFL lines are listed below and SportsLine’s advanced computer model includes all the NFL betting advice and predictions you need to start making the best Week 1 NFL picks now.

The model, which simulates every NFL game 10,000 times, has grown to over $7,500 for top-rated $100 players NFL selection since its inception. The model kicks off the 2022 NFL season with an incredible 138-97 run of top-flight NFL picks, stretching back to the 2017 season. Amazingly, it hasn’t missed out on a top-flight pick since week 15 of last season.

The model has also ranked in the top 10 on NFLPickWatch for four of the last six years in direct NFL picks, beating more than 94 percent of CBS Sports football pick ’em players four times in that span. Whoever followed it is way up.

Now it has turned its attention to the latest Week 1 NFL Odds by Caesars and suspended picks for every NFL matchup. Go here to see each selection.

The best NFL predictions for week 1

One of the best Week 1 NFL predictions recommended by the model: The Vikings (+2) cover well over 50 percent of the simulations against the Packers. Minnesota has both won and covered in two of their last three games in this divisional rivalry. Additionally, the Vikings were 2-1 home underdogs last year while the Packers were 2-3 away favorites.

The Vikings have continuity with their key offensive pieces and will also get back the tight end from Irv Smith Jr. who missed all of last year. On the other hand, Green Bay is working on several new receivers and Aaron Rodgers has publicly called out many of his young wideouts. The model has Green Bay’s top two receivers, Allen Lazard and Christian Watson, who fail to combine as many yards as star WR Justin Jefferson himself has. SportsLine’s advanced model predicts the Vikings (+1.5) to cover well over 50 percent of the time at home. See who else supports here.

Another Week 1 NFL prediction: The Colts (-8) cover the spread on the road against the Texans. One of Houston’s many weaknesses over the past year was run defense, which ranked No. 31. That porous defense was one of the main reasons Jonathan Taylor was the attacking king, as he gained 145 yards against Houston in Week 6 and another 143 yards in Week 13. The model modestly predicts that Taylor has just 110 yards, but it also has Colts quarterback Matt Ryan throwing for nearly 250 yards and two touchdowns.

After a total of three points in the two games against Indy in 2021, the model sees Houston hitting double digits in Week 1. That won’t be enough against a Colts team that’s forecast to surpass their season average of 26.5 points per game a year ago. SportsLine’s model lets Indianapolis win by double digits in almost 60 percent of the simulations and cover it as an eight-point favorite. See which other teams you should pick here.

How to make NFL picks for week 1

The model has also questioned who wins and covers in every other game on the NFL Week 1 schedule and calls for a Super Bowl contender to go down hard. You can get every selection for every game only at SportsLine.

So what NFL tips can you hit with confidence? And which Super Bowl contender goes down hard? Then check out the latest NFL odds below Visit SportsLine to see which teams are winning and cover the range, all from a proven computer model that has grossed over $7,500 since inceptionand find out.

Week 1 NFL odds, lines, spreads

Get full NFL picks at SportsLine

Thursday, September 8th

Aries at Bills (+2.5, 53)

Featured Game | Los Angeles Rams vs. Buffalo Bills

Sunday September 11th

Ravens at Jets (+7, 44.5)

Featured Game | New York Jets vs. Baltimore Ravens

Browns at Panthers (-1.5, 41.5)

Featured Game | Carolina Panthers vs. Cleveland Browns

Colts at Texans (+8, 44)

Featured Game | Houston Texans vs. Indianapolis Colts

Jaguars at Commanders (-3. 44)

Featured Game | Washington Commanders vs. Jacksonville Jaguars

Patriots at Dolphins (-2.5, 45)

Featured Game | Miami Dolphins vs. New England Patriots

Saints at Falcons (+5.5, 42.5)

Featured Game | Atlanta Falcons vs. New Orleans Saints

Eagle near Lions (+4, 48.5)

Featured Game | Detroit Lions vs Philadelphia Eagles

Steelers at Bengals (-6.5, 44.5)

Featured Game | Cincinnati Bengals vs. Pittsburgh Steelers

49ers at Bears (+7, 42)

Featured Game | Chicago Bears vs. San Francisco 49ers

Packers at Vikings (+2, 48)

Featured Game | Minnesota Vikings vs. Green Bay Packers

Chiefs at Cardinals (+3.5, 53)

Featured Game | Arizona Cardinals versus Kansas City Chiefs

Raiders at Chargers (-3.5, 52)

Featured Game | Los Angeles Chargers vs. Las Vegas Raiders

Giants on Titans (-5.5, 44)

Featured Game | Tennessee Titans vs. New York Giants

Privateers at Cowboys (+1.5, 50)

Featured Game | Dallas Cowboys vs. Tampa Bay Buccaneers

Monday 12 September

Broncos at Seahawks (+6, 41.5)

Featured Game | Seattle Seahawks vs. Denver Broncos NFL Odds, Lines, Tips, Spreads, Best Bets, Predictions for Week 1, 2022: Model Loving Vikings, Colts

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