Scientists are sounding the alarm about little-known STDs in the US that are resistant to ANY antibiotic

It is feared that a “silent spread” of STIs that can cause infertility is developing into a superbug.

Mycoplasma genitalium, also known as M. genitalium or M. gen, is on the way to becoming resistant to all the antibiotics used to treat it.

The sexually transmitted infection was first discovered in London in the 1980s – but a test has only been available in the US since 2019.

It means scientists aren’t sure how widespread it is.

Some studies suggest that just one in 100 US adults will test positive for the virus, but experts estimate that up to a fifth will get it at some point in their lives.

The bacterial infection has been linked to infertility, premature birth and miscarriage, as well as cervical swelling and pelvic inflammatory disease.

There is increasing concern that it is becoming untreatable because the STI has developed resistance to the most popular antibiotic used to treat STIs, azithromycin, as well as quinolone, macrolide and doxycycline.

Alternatives are available, but they cause serious side effects, meaning they are not suitable for pregnant women. And there are signs that it is already becoming more tolerant towards them as well.

There are also fears that M. gen is becoming more common as STIs are on the rise in the US overall.

There was a record 2.5 million infections in 2021, up from 2.4 million in 2020, itself an all-time high.

In 2018, the CDC estimated the number of sexually transmitted infections in the U.S. on any given day that year was nearly 68 million.

Superbugs are estimated to contribute to about 7 million deaths a year, with some experts warning they should be taken just as seriously as global warming.

Mycoplasma genitalium, also known as M. genitalium or M. gen, causes serious symptoms including infertility but is resistant to four different types of antibiotics. It is estimated that up to one in five sexually active US citizens could be affected

Mycoplasma genitalium, also known as M. genitalium or M. gen, causes serious symptoms including infertility but is resistant to four different types of antibiotics. It is estimated that up to one in five sexually active US citizens could be affected

Mycoplasma genitalium, also known as M. genitalium or M. gen, causes serious symptoms including infertility but is resistant to four different types of antibiotics. It is estimated that up to one in five sexually active US citizens could be affected

What is M. gen.?

Mycoplasma genitalium, also known as M. genitalium or M. gen., is a sexually transmitted disease.

It is a bacterial infection that infects the urinary and genital tracts of both men and women.

First discovered in London in the 1980s, it is passed on through sexual contact.

Babies can also get it from their mothers before they are born through the amniotic fluid.

It’s more common in young people and also in people who have unprotected sex and have multiple sex partners (although this is true for all STIs).

The infection is similar to chlamydia but is caused by a different bacterium.

Past M. gen. cases may have been mistaken for chlamydia and treated as chlamydia, leading to the gradual development of resistance to various antibiotics.

However, it is possible to have both infections.

A test for M. gen. has only been available in the US since 2019.

Routine screening is not recommended by the CDC.

Symptoms include:

  • bleeding and swollen genitals
  • Urethritis, swelling and irritation of the urethra, making urination painful
  • Abnormal discharge
  • Cervical swelling
  • Pelvic inflammatory disease (PID) in women, causing lower abdominal pain and bleeding after sex

Professor Paul Hunter, an infectious disease expert at the University of East Anglia in England, told DailyMail.com: “This is one of a few genital mycoplasma, including M. gen., M. hominis and some related ureaplasma, M. gen. has the strongest evidence that it has adverse health effects.’

The STI is also “difficult to diagnose,” meaning it travels under the radar, he said.

“It’s not easy to do anything about it because the infection is fairly common and most infections don’t have any adverse health consequences.”

M. gen can cause painful, bleeding, and swollen genitals and even infertility in women.

But many people show no symptoms at all and can carry it for years without realizing it.

It can be transmitted before birth through genital-to-genital contact, such as unprotected vaginal or anal sex, and mother-to-child transmission.

The risk of preterm birth almost doubled in women with M. gen., an analysis of 10 studies up to 2021, published in May in the journal Sexually Transmitted Infection, found.

In males, M. gen. can cause urethritis, swelling and irritation of the urethra, making urination painful, but more research is needed to determine the long-term effects of M. gen. Infection.

It can also cause abnormal discharge in both sexes.

Simon Clarke, associate professor of cellular microbiology at the University of Reading, told DailyMail.com it was “quite feasible” for M. gen to become fully resistant to antibiotics.

However, he said several drug-resistant strains were likely “some distance away”.

He said “silent dissemination” is the problem, as people “don’t know to get tested and they’re passing it along to someone else.”

This means it will continue to become more dominant and doctors will continue to prescribe antibiotics to treat it, promoting antibiotic resistance and the potential for M. gene. to become a superbug.

It comes amid rising STI rates across the board. The chlamydia rate, the most common STI in the US, has been rising for over 30 years

It comes amid rising STI rates across the board. The chlamydia rate, the most common STI in the US, has been rising for over 30 years

It comes amid rising STI rates across the board. The chlamydia rate, the most common STI in the US, has been rising for over 30 years

M. gen., chlamydia, and gonorrhea can all be asymptomatic, meaning the STI is silently spreading. Gonorrhea rates peaked in the 1970s but still remain high

M. gen., chlamydia, and gonorrhea can all be asymptomatic, meaning the STI is silently spreading. Gonorrhea rates peaked in the 1970s but still remain high

M. gen., chlamydia, and gonorrhea can all be asymptomatic, meaning the STI is silently spreading. Gonorrhea rates peaked in the 1970s but still remain high

What is antibiotic resistance?

Antibiotics have been unnecessarily handed out by doctors for decades, turning once-harmful bacteria into superbugs.

The World Health Organization (WHO) has previously warned that if nothing is done, the world is heading for a “post-antibiotics” era.

It was claimed that without immediate solutions to the growing crisis, common infections like chlamydia would become killers.

Bacteria can become resistant if antibiotics are administered incorrectly or unnecessarily.

Former UK Medical Director Dame Sally Davies claimed in 2016 that the threat of antimicrobial resistance was as serious as terrorism.

Figures estimate that superbugs will kill 10 million people each year by 2050, with patients succumbing to the once harmless bugs.

Around 700,000 people worldwide die each year from drug-resistant infections such as tuberculosis (TB), HIV and malaria.

Again and again it was feared that medicine would be taken back to the “dark ages” when antibiotics would become ineffective in the years to come.

Aside from existing drugs becoming less effective, only one or two new antibiotics have been developed in the last 30 years.

In September 2017, the WHO warned that antibiotics were “running out” when a report found a “serious shortage” of new drugs in the development pipeline.

Without antibiotics, caesarean sections, cancer treatments and hip replacements would be incredibly “risky”, it was said at the time.

It is estimated that superbugs kill 7 million each year, either as co-infection or directly.

But a major study last year found they are the leading cause of 1.2 million deaths a year worldwide.

This would make superbugs a bigger global killer than AIDS or malaria, which killed 860,000 and 640,000 people respectively that year. In comparison, Covid killed an estimated 3.5 million people in 2021.

The Centers for Disease Control and Prevention (CDC) does not recommend routine screening for M. gen. and does not state why.

Because the test, known as the Aptima nucleic acid amplification test, was only approved in 2019, it has not been widely used and physicians are not required to report cases of the infection.

Patients are screened for M. gen. only. after persistent symptoms and negative tests for other STIs.

So there is no clear picture of how common M. gen. is or who it affects most.

But Lisa Manhart, a professor of epidemiology at the University of Washington School of Public Health, told NBC News that M.gen. could affect up to 20 percent of sexually active women and 17 percent of men between the ages of 15 and 24.

In contrast, the most common STI in the US is chlamydia, with 5 percent of sexually active women ages 14 to 24 being infected with the STI.

When conventional antibiotics don’t work, doctors can use moxifloxacin.

This works but causes significant side effects, including nausea, diarrhea, dizziness, and vomiting.

This means that it is not a suitable treatment for everyone, especially pregnant women.

And the more moxifloxacin is used to treat M. gen., the more likely it is to become resistant to it as well.

Aside from moxifloxacin, treatment options are limited.

The CDC currently recommends testing for antibiotic resistance before deciding which drugs to take, but these tests are not FDA-approved.

Few specialized research centers can test whether the infection is resistant to an antibiotic.

Widely available versions of the test could take years, as could antibiotics that work.

Meanwhile, during the Centers for Disease Control and Prevention’s conference on STD prevention Monday, Executive Director of the National Coalition of STD Directors David Harvey said the rise in STIs is “out of control.”

Infection rates for sexually transmitted diseases including gonorrhea and syphilis have been rising for years, but last year syphilis cases hit the highest level since 1948.

Source: | This article originally belongs to Dailymail.co.uk


https://www.soundhealthandlastingwealth.com/health-news/scientists-sound-alarm-over-little-known-sti-in-us-resistant-to-every-antibiotic-used-against-it/ Scientists are sounding the alarm about little-known STDs in the US that are resistant to ANY antibiotic

Brian Ashcraft

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